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De Profundis means literally 'Out of the Depths' in Latin and is taken from the first line of Psalm 130.
In Rome, the "De Profundis" is rung every evening by the parish churches one hour after the Ave Maria. Clement XII in 1736 granted an indulgence for this practice and endeavored to extend it. This custom is observed in many other places, particularly in North America.
At 9 o'clock every evening, a nine-count slow toll is rung, one toll for each line of the prayer.